Distribution of blood flow in the renal cortex during saline loading.

Effect of hemodilution on the distribution of renal blood flow.

We evaluated the effects of hemodilution, expansion of intravascular volume, and expansion of interstitial volume on the distribution of cortical renal blood flow, utilizing the microsphere technique. Hemodilution without volume expansion (saline exchange) produced an increase in fractional blood flow in zone 1 (outermost zone) of the cortex from 34 plus or minus 1% to 43 plus or minus 2% and a...

Intrarenal distribution of blood flow during elevation of ureteral pressure in dogs.

The ^Kr method was used to determine the effect of elevated ureteral pressure on total cortical and outer medullary nutrient renal blood flow of pentobarbital-anesthetized dogs. Increased ureteral pressure during mild saline diuresis resulted in increased total nutrient blood flow from 316 to 402 ml/100 g/min. Autoradiographs demonstrated that the increased blood flow is confined to the renal c...

Changes in Renal Blood Flow and Possibly the Intrarenal Distribution of Blood during the Natriuresis Accompanying Saline Loading in the Dog.

Cortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice.

The effect of acutely increasing renal perfusion pressure or extracellular fluid volume on renal medullary and cortical blood flow was examined in the low-renin deoxycorticosterone acetate (DOCA)-salt hypertension model in mice. A 50-mg DOCA tablet was implanted, and 1% saline was given as drinking water for 3 wk. Medullary and cortical blood flow were determined with laser-Doppler flowmetry, a...

Increased renal tubular sodium reabsorption during exercise-induced hypervolemia in humans.

We tested the hypothesis that renal tubular Na(+) reabsorption increased during the first 24 h of exercise-induced plasma volume expansion. Renal function was assessed 1 day after no-exercise control (C) or intermittent cycle ergometer exercise (Ex, 85% of peak O(2) uptake) for 2 h before and 3 h after saline loading (12.5 ml/kg over 30 min) in seven subjects. Ex reduced renal blood flow (p-ami...